ONCE-WEEKLY MAZDUTIDE IN ADULTS WITH OBESITY OR OVERWEIGHT
Abstract
This thesis is based on a phase 3, double-blind, placebo-controlled trial that investigated the efficacy and safety of mazdutide, a once-weekly glucagon-like peptide-1 and glucagon receptor dual agonist, in adults with obesity or overweight. The study demonstrated significant and clinically relevant weight reduction over a 32- and 48-week period, along with improvements in cardiometabolic risk factors. Gastrointestinal adverse events were most common but generally mild or moderate in severity.
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References
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