NEYRODEGENERATSIYA MEXANIZMLARI: ALTSGEYMER KASALLIGIDA HUJAYRA O`LIM JARAYONLARI
Keywords:
Altsgeymer, neyrodegeneratsiya, beta-amiloid, tau-oqsili, demensiya, oksidlovchi stress, klinik belgilari. Altsgeymer kasalligi, Aβ-peptid, mitoxondriya neyrodegeneratsiya, APOE4.Abstract
Ushbu tezisda Altsgeymer kasalligining tarqalishi, asosiy patogenezi, molekulyar mexanizmlari, klinik ko‘rinishlari va davolash tamoyillari yoritib beriladi. Kasallikning rivojlanishida beta-amiloid to‘planishi, tau-oqsili giperfosforillanishi, oksidlovchi stress va neyroinflammatsiya kabi omillarning o‘zaro bog‘liqligi ilmiy asoslangan holda tahlil qilindi.
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