CLINICAL COURSE RHEUMATOID ARTHRITIS DEPENDING ON DAS28 ACTIVITY AND LEVELS OF TNF-Α AND IL-6

Authors

  • Bekmirzaev A.E. Tashkent State Medical University Termez Branch1, Author
  • Akhmedov Kh.S Tashkent State Medical University2 Author
  • Khalmetova F.I. Tashkent State Medical University2 Author

Keywords:

Assess the clinical course of RA depending on the activity of DAS28 and the levels of TNF-α and IL-6 in blood serum.

Abstract

Rheumatoid arthritis (RA) is a systemic autoimmune disease with chronic progressive inflammation that leads to structural joint damage and disability. The pathogenesis is based on cytokine-mediated mechanisms, including the hyperproduction of Tumor necrosis factor alpha (TNF-α) and Interleukin 6 (IL-6), which determine the disease's activity. A key tool for objectively assessing the severity of RA is the Disease Activity Score 28 (DAS28) activity index.

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Published

2025-10-01

Issue

Vol. 4 No. 50 (2025): PEDAGOGICAL SCIENCES AND TEACHING METHODS

Section

Articles