NEYROMEDIATORLAR BIOSINTEZI: AHAMIYATI VA KASALLIKLARI
Keywords:
Neyromediatorlar, biosintez, asab tizimi, dopamin, serotonin, asetilxolin, GABA.Abstract
Ushbu maqolada neyromediatorlarning biosintezi, ularning asab tizimidagi funksional ahamiyati hamda biosintez jarayonidagi buzilishlar sabab bo‘ladigan kasalliklar keng yoritilgan. Dopamin, serotonin, asetilxolin va GABA kabi asosiy neyromediatorlarning sintez mexanizmlari, ularni shakllantiruvchi fermentlar va metabolik bosqichlar izohlangan. Shuningdek, ularning yetishmovchiligi yoki ortiqcha ishlab chiqarilishi natijasida yuzaga keladigan Parkinson kasalligi, depressiya, shizofreniya, Altsgeymer kasalligi va epilepsiya kabi klinik holatlar tahlil qilingan. Tadqiqot neyromediator biosintezining normal asab tizimi faoliyatini saqlash va nevrologik kasalliklarni erta aniqlashdagi muhim o‘rnini ko‘rsatadi.
Downloads
References
- Kandel E.R., Schwartz J.H., Jessell T.M. Principles of Neural Science. — McGraw-Hill, 2013.
- Purves D., Augustine G.J., Fitzpatrick D. Neuroscience. — Oxford University Press, 2018.
- Alberts B. Molecular Biology of the Cell. — Garland Science, 2015.
- Bear M.F., Connors B.W., Paradiso M.A. Neuroscience: Exploring the Brain. — Lippincott Williams & Wilkins, 2020.
- Stahl S.M. Stahl’s Essential Psychopharmacology. — Cambridge University Press, 2017.
- Siegel G.J., Albers R.W. Basic Neurochemistry: Molecular, Cellular and Medical Aspects. — Academic Press, 2014.
- Bloom F.E., Nelson C.A. Psychopharmacology and Biological Psychiatry. — Oxford University Press, 2016
