THE PHYSIOLOGY, EPIDEMIOLOGY, CLINICAL MANIFESTATIONS, LABORATORY DIAGNOSIS, AND MANAGEMENT OF IRON DEFICIENCY AND IRON DEFICIENCY ANAEMIA IN CHILDREN.
Keywords:
Iron; iron deficiency; iron deficiency anaemia; children; treatmentAbstract
The purpose of this review article is to explain the physiology, epidemiology, aetiology, clinical effects, laboratory diagnosis, and management of iron deficiency and iron deficiency anaemia in children.
References
World Health Organization. Iron Deficiency Anemia: Assessment, Prevention, and Control- A Guide for Program Managers. Geneva, Switzerland: World Health Organization; 2001. WHO/NHD/01.3
Cairo G, Bernuzzi F, Recalcati S. A precious metal: Iron, an essential nutrient for all cells. Genes Nutr 2006;1:25-39.
Rosove MH, Perloff JK, Hocking WG, et al. Chronic hypoxaemia and decompensated erythrocytosis in cyanotic congenital heart disease. Lancet 1986;2:313-5.
Verel D. Blood volume changes in cyanotic congenital heart disease and polycythemia rubra vera. Circulation 1961;23:749-53.
Tempe DK, Virmani S, Rigler B, et al. Coagulation abnormalities in patients with cyanotic congenital heart disease. J Cardiothorac Vasc Anesth 2002;16:752-65.
Oechslin E. Hematological management of the cyanotic adult with congenital heart disease. Int J Cardiol 2004;97:109-15.
Lozoff B, Jimenez E, Wolf AW. Long-Term Developmental Outcome of Infants with Iron Deficiency. N Engl J Med 1991;325:687-94.
Kochanowski BA, Sherman AR. Cellular growth in iron-deficient rats: effect of pre- and postweaning iron repletion. J Nutr 1985;115:279-87.
Ogunkunle OO. Erythrocyte indices of iron status in children with cyanotic congenital heart disease at the University College Hospital, Ibadan. Niger J Paed 2013;40:75-8
Kaemmerer H, Fratz S, Braun SL, et al. Erythrocyte indexes, iron metabolism, and hyperhomocysteinemia in adults with cyanotic congenital cardiac disease. Am J Cardiol 2004;94:825-8.