FOLIC ACID USE IN PRE-SCHOOL CHILDREN WITH EPILEPSY
Keywords:
epilepsy, folic acid, children under school age.Abstract
The condition of 70 children with epilepsy was studied. 38 (54.3%) children (Group I) received folacin (folic acid) at the recommended dose of 5 mg per day. 32 (45.7%) children (Group II of the study) did not take the drug for various socio-economic reasons. The level of folates in erythrocytes and the level of homocysteine in venous blood plasma were studied in children of three study groups. According to the results of homocysteine in the groups, it was noted that the concentration was distributed as follows: II - 10.5 ± 0.3 μmol / l, and in the control - 5.1 ± 0.1 μmol / l, which shows significant hyperhomocysteinemia in groups with epilepsy, while a positive effect on this indicator is noted for folic acid intake at a dose of 5 mg per day (Folacin). The study revealed a direct link between the use of folic acid and the level of pathology detected in the process of neuropsychic development of children.
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