A MULTIDISCIPLINARY APPROACH TO THE DIAGNOSIS AND TREATMENT OF ATYPICAL TOPHACEOUS GOUT

Abstract

Gout is a chronic disease associated with impaired uric acid metabolism. The primary clinical manifestations of gout include recurrent acute arthritis and the formation of gouty nodules (tophi). Tophi are deposits of uric acid crystals surrounded by granulomatous tissue. A vital laboratory indicator in gout is elevated uric acid levels (hyperuricemia), which contribute to the progression of comorbid conditions in patients, such as coronary artery disease, dyslipidemia, and type 2 diabetes mellitus. The development of tophi is generally observed in cases of prolonged or poorly controlled hyperuricemia. Management of uric acid levels involves dietary modifications and urate-lowering medications.