FERTIL YOSHDAGI AYOLLARDA GIPERPROLAKTINEMIYANING INSULINOREZISTENTLIKGA TA`SIRI.
Keywords:
giperprolaktinemiya; insulinorezistentlik; metabolik sindromAbstract
Giperprolaktinemiya (GP) - bu qondagi prolaktin gormoni darajasi normaga nisbatan yuqori bo'lgan holat.Bu sindrom eng keng tarqalgan klinik endokrinologiya muammolaridan biridir. Kattalar aholisining 0,4% ni GP bilan kasallangan bemorlar tashkil qiladi. Reproduktiv kasalliklar ichida esa 9-17% ayollar kasallanadi. Insulin rezistentlik (IR)- endogen yoki ekzogen insulinga metabolik javobning buzilishi.Insulinorezistentlik tarqalishi, ayniqsa, rivojlanayotgan mamlakatlarda va yosh populyatsiyalarda 20% dan 40% gacha ortmoqda. Odatda plazmada prolaktin miqdorining ortishi insulinorezistentlik fenomeni bilan birga keladi.
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References
Majumdar A, Mangal NS. Hyperprolactinemia. J Hum Reprod Sci. 2013; 6(3): 168–175, doi: 10.4103/0974-1208.121400, indexed in Pubmed: 24347930.
Biller BM, Luciano A, Crosignani PG, et al. Guidelines for the diagnosis and treatment of hyperprolactinemia. J Reprod Med. 1999; 44(12 Suppl): 1075–1084, indexed in Pubmed: 10649814.
Prasad DS, Kabir Z, Dash AK, et al. Prevalence and risk factors for metabolic syndrome in Asian Indians: A community study from urban Eastern India. J Cardiovasc Dis Res. 2012; 3(3): 204–211, doi: 10.4103/0975-3583.98895, indexed in Pubmed: 22923938.
Ford ES, Li C, Zhao G, et al. Prevalence of the metabolic syndrome among U.S. adolescents using the definition from the International Diabetes Federation. Diabetes Care. 2008; 31(3): 587–589, doi: 10.2337/dc07-1030, indexed in Pubmed: 18071007.
James D, Umekwe N, Edeoga C, et al. Multi-year reproducibility of hyperinsulinemic euglycemic clamp-derived insulin sensitivity in free-living adults: Association with incident prediabetes in the POP-ABC study. Metabolism. 2020; 109: 154263, doi: 10.1016/j.metabol.2020.154263, indexed in Pubmed: 32445642.
Gastaldelli A, Gaggini M, DeFronzo RA. Role of Adipose Tissue Insulin Resistance in the Natural History of Type 2 Diabetes: Results From the San Antonio Metabolism Study. Diabetes. 2017; 66(4): 815–822, doi: 10.2337/db16-1167, indexed in Pubmed: 28052966.
Cree-Green M, Bergman BC, Coe GV, et al. Hepatic steatosis is common in adolescents with obesity and PCOS and relates to de novo lipogenesis but not insulin resistance. Obesity (Silver
Spring). 2016; 24(11): 2399–2406, doi: 10.1002/oby.21651, indexed in Pubmed: 27804265.
Qaid M, Abdelrahman M. Role of insulin and other related hormones
in energy metabolism — A review. Cogent Food Agriculture. 2016; 2(1), doi: 10.1080/23311932.2016.1267691.
DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol. 1979; 237(3): E214–E223, doi: 10.1152/ajpendo.1979.237.3.E214, indexed in Pubmed: 382871.
Cree-Green M, Newnes L, West A, et al. Insulin resistance, but not excess liver fat, is relatedto hyperandrogenism in adolescent PCOS. Paper presented at Endocrine Society Annual Meeting; June 1, 2014; Washington, DC.
Gierach M, Gierach J, Junik R. Insulin resistance and thyroid disorders. Endokrynol Pol. 2014; 65(1): 70–76, doi: 10.5603/EP.2014.0010, indexed in Pubmed: 24549605.
Brown AE, Walker M. Genetics of Insulin Resistance and the Metabolic Syndrome. Curr Cardiol Rep. 2016; 18(8): 75, doi: 10.1007/s11886-016-0755-4, indexed in Pubmed: 27312935.
Kim JK. Hyperinsulinemic-euglycemic clamp to assess insulin sensitivity in vivo. Methods Mol Biol. 2009; 560: 221–238, doi: 10.1007/978-1- 59745-448-3_15, indexed in Pubmed: 19504253.
Owei I, Jain N, Jones D, et al. Physiology of Glycemic Recovery and Stabilization After Hyperinsulinemic Euglycemic Clamp in Healthy Subjects. J Clin Endocrinol Metab. 2018; 103(11): 4155–4162, doi: 10.1210/jc.2018-01569, indexed in Pubmed: 30239760.
Carreau AM, Xie D, Garcia-Reyes Y, et al. Good agreement between hyperinsulinemic-euglycemic clamp and 2 hours oral minimal model assessed insulin sensitivity in adolescents. Pediatr Diabetes. 2020; 21(7): 1159–1168, doi: 10.1111/pedi.13072, indexed in Pubmed: 32592269.
Eldin AWJ. Natural history of ROHHAD syndrome: development of severe insulin resistance and fatty liver disease over time. Clin Diabetes.
Cali AMG, Man CD, Cobelli C, et al. Primary defects in beta-cell exacerbated by worsening of insulin resistance mark the development of impaired glucose tolerance in obese adolescents.
Diabetes Care. 2009; 32(3): 456–461, doi: 10.2337/dc08-1274, indexed in Pubmed: 19106382.
Soop M, Nygren J, Brismar K, et al. The hyperinsulinaemic‒euglycaemic glucose clamp: reproducibility and metabolic effects of prolonged insulin infusion in healthy subjects. Clinical Science. 2000; 98(4): 367–374, doi: 10.1042/cs19990268, indexed in Pubmed: 10731469.
Le DS, Brookshire T, Krakoff J, et al. Repeatability and reproducibility of the hyperinsulinemic-euglycemic clamp and the tracer dilution technique in a controlled inpatient setting. Metabolism. 2009; 58(3): 304–310, doi: 10.1016/j.metabol.2008.09.029, indexed in Pubmed: 19217443.
Bokemark L, Frödén A, Attvall S, et al. The euglycemic hyperinsulinemic clamp examination: variability and reproducibility. Scand J Clin Lab Invest. 2000; 60(1): 27–36, doi: 10.1080/00365510050185010, indexed in Pubmed: 10757451.
Finucane FM, Luan J, Wareham NJ, et al. (on behalf of the European Group for the Study of Insulin Resistance: Relationship between Insulin Sensitivity and Cardiovascular Disease Risk Study Group). Correlation of the leptin:adiponectin ratio with measures of insulin resistance
in non-diabetic individuals. Diabetologia. 2009; 52(11): 2345–2349, doi: 10.1007/s00125-009-1508-3, indexed in Pubmed: 19756488.
Pacini G, Mari A. Methods for clinical assessment of insulin sensitivity and beta-cell function. Best Pract Res Clin Endocrinol Metab. 2003; 17(3): 305–322, doi: 10.1016/s1521-690x(03)00042-3, indexed in Pubmed: 12962688.
Abdul-Ghani MA, Matsuda M, Balas B, et al. Muscle and liver insulin resistance indexes derived from the oral glucose tolerance test. Diabetes Care. 2007; 30(1): 89–94, doi: 10.2337/dc06-1519, indexed in Pubmed: 17192339.
Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care. 1999; 22(9): 1462–1470, doi: 10.2337/diacare.22.9.1462, indexed in Pubmed: 10480510.
Galofré JC, Pujante P, Abreu C, et al. Relationship between thyroid-stimulating hormone and insulin in euthyroid obese men. Ann Metab. 2008; 53(3-4): 188–194, doi: 10.1159/000172981, indexed in Pubmed: 19011282.
Roos A, Bakker SJL, Links TP, et al. Thyroid function is associated with components of the metabolic syndrome in euthyroid subjects. J Clin in Pubmed: 17090642.
Tesić D, Pantelinac P, Radosavljević J, et al. [Hashimoto’s hypothyroidism associated with insulin resistance in type 2 diabetes]. Med Pubmed: 17066592.
Pallotti S, Gasbarrone S, Franzese IT. Relationship between insulin secretion, and thyroid and ovary function in patients suffering from polycystic ovary. Minerva Endocrinol. 2005; 30(3): 193–197, indexed in Pubmed: 16208308.
Diamanti Kandarakis E, Alexandraki K, Piperi C, et al. Inflammatory and endothelial markers in women with polycystic ovary syndrome. Eur J Clin Invest. 2006; 36(10): 691–697, doi: 10.1111/j.1365-2362.2006.01 712.x, indexed in Pubmed: 16968464.
Bahceci M, Tuzcu A, Bahceci S, et al. Is hyperprolactinemia associated with insulin resistance in non-obese patients with polycystic ovary syndrome? J Endocrinol Invest. 2003; 26(7): 655–659, doi: 10.1007/BF03347025, indexed in Pubmed: 14594118.
