EXPERIMENTAL SUBSTANTIATION OF THE USE OF HYPOXIA-INDUCIBLE FACTOR (HIF-1Α) FOR THE DEVELOPMENT OF TOXIC HEPATITIS.
Abstract
This work is dedicated to the experimental study of the role of hypoxia-inducible factor 1 (HIF-1α) in the development and course of toxic hepatitis induced by heliotrin intoxication. Heliotrin is a pyrrolizidine alkaloid known for its toxic properties, especially to the liver. The study aims to examine changes in HIF-1α levels as a potential marker of oxygen deficiency in the liver and its involvement in the pathogenesis of toxic hepatitis
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Бабаджанов А. С. и др. Патология коагуляционного гемостаза при циррозе печени и COVID-19 //Вестник Ташкентской медицинской академии. – 2021. – №. 1. – С. 15-16.
Курбонова З.Ч. Нарушение сосудисто– тромбоцитарного звена гемостаза у больных с хроническими гепатитами и циррозом печени вирусной этиологии // Журнал проблемы биологии и медицины. – 2018. – № 3 (102). – С. 40–43.
Tairova G. B., Ch K. Z. Improvement Of Laboratory Diagnosis Of Autoimmune Hepatitis //Galaxy International Interdisciplinary Research Journal. – 2022. – Т. 10. – С. 1667-1671.
Каримов Х.Я., и др. Механизмы нарушений при токсическом повреждении печени и пути их коррекции с помощью нового аминокислотного раствора на основе сукцината натрия и маннитола // Журнал теоретической и клинической медицины-2021. - №3.
Сайфутдинова З.А. Современные представления о гипоксии-индуцибельном факторе-1 (hif-1) – важном звене в патогенезе ишемических повреждений тканей // Вестник Ташкентской медицинской академии-2021. - №3.
Сайфутдинова З.А., Каримов Х.Я., Саидов А.Б. Патофизиологическое обоснование применения новой аминокислотной смеси при повреждении печени // Тиббиётда янги кун-2021. - №4. –Б. 93-96.
Negmatov, S., Rahmonov, B., Sobirov, B., Abdullaev, A., Salimsakov, Y., Negmatov, J., ... & Mahkamov, D. (2012). Developing of Effective Multipurpose Polymer-Bitumen Compositions. Advanced Materials Research, 413, 539-540.
Negmatov, S., Rahmonov, B., Sobirov, B., Abdullaev, A., Salimsakov, Y., Negmatov, J., ... & Mahkamov, D. (2012). Developing of Effective Multipurpose Polymer-Bitumen Compositions. Advanced Materials Research, 413, 539-540.
Baxtiyorovich, R. B. (2025). SIYDIK TOSH KASALLIGINING EPIDEMIOLOGIYASI. PEDAGOGICAL SCIENCES AND TEACHING METHODS, 4(43), 428-430.
Baxtiyor o'g'li, R. B. (2024). POSTOPERATIVE COMPLICATIONS OF BENIGN PROSTATIC HYPERPLASIA: A COMPREHENSIVE REVIEW. Interdisciplinary Journal of Chemical Biology and Medicine, 1(1), 27-28.
Raxmonov, S. (2025). THE ROLE OF CLINICAL LABORATORY AND PATHOLOGICAL PHYSIOLOGY IN DETERMINING ANTI-NUCLEAR ANTIBODIES (ANK) TITER. International journal of medical sciences, 1(2), 311-315.
Oybek o‘g‘li, R. S. O’TKIR LEYKOZNING MOLEKULYAR DIAGNOSTIKASIDAGI AXAMIYATI.
Raxmonov, S. (2025). O’TKIR LEYKOZNING MOLEKULYAR DIAGNOSTIKASIDAGI AXAMIYATI. Modern Science and Research, 4(3), 1683-1690.
Oybek o’g’li, R. S. (2025, February). THE ROLE OF NEOROTRANSMITTERS IN PAIN AND ITS MANAGEMENT IN THE BODY. In International Conference on Modern Science and Scientific Studies (pp. 318-322).
Oybek o’g’li, R. S. (2024). THE IMPORTANCE OF LABORATORY RESULTS IN THE TREATMENT OF LIVER DISEASE. Multidisciplinary and Multidimensional Journal, 3(10), 67-74.
Raxmonov, S. (2025). ANTI-TUOR IMMUNITY. ONCOMARKERS. Modern Science and Research, 4(3), 637-642.
Oybek o'g'li, R. S. (2025). ANTI-TUOR IMMUNITY. ONCOMARKERS.
Oybek o’g’li, R. S. (2025). CANCER NOMENKLATURE AND SUSTAINED PROLIFERATIVE SIGNALING. Web of Medicine: Journal of Medicine, Practice and Nursing, 3(2), 413-417.
