FREQUENCY OF BETA-THALASSEMIA IN THE REPUBLIC OF UZBEKISTAN

Abstract

Thalassemia is an inherited blood disorder that affects the production of hemoglobin, a protein found in red blood cells that is responsible for transporting oxygen throughout the body. There are several types of thalassemia, the most common being alpha and beta thalassemia. Beta thalassemia is a hereditary disease associated with impaired synthesis of hemoglobin beta chains. The incidence of beta thalassemia may vary by region and ethnic group. In Uzbekistan, as in other countries with high levels of migration and mixing of ethnic groups, beta thalassemia can occur with varying frequencies. According to various studies, the carriage rate of beta thalassemia in some regions can reach 5-10% or higher, especially among the Uzbek population and other ethnic groups living in the country.