LABORATORY DIAGNOSIS OF VITAMIN D DEFICIENCY IN PATIENTS WITH CHRONIC PANCREATITIS USING THE AFIAS ANALYZER
Abstract
Chronic pancreatitis is accompanied by progressive exocrine pancreatic insufficiency, leading to impaired digestion and absorption of fats, as well as fat-soluble vitamins, including vitamin D. Vitamin D deficiency in this category of patients is associated with the development of osteopenia and osteoporosis, necessitating timely laboratory diagnosis.
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References
Holick MF Vitamin D deficiency. N Engl J Med. 2007;357(3):266–281. doi:10.1056/NEJMra070553.
Lindkvist B., Dominguez-Munoz E., Luaces-Regueira M., et al. High prevalence of vitamin D deficiency in chronic pancreatitis: relation to bone mineral density and pancreatic exocrine function. Pancreatology. 2011;11(5):513–519. doi:10.1159/000329606.
Duggan SN, O'Sullivan M., O'Morain C. Vitamin D deficiency in chronic pancreatitis: a systematic review. World J Gastroenterol. 2013;19(44):7917–7924. doi:10.3748/wjg.v19.i44.7917.
Martinsen TC, Seierstad T, Hveem K, et al. Prevalence of vitamin D deficiency in patients with chronic pancreatitis: a cross-sectional study. Front Pharmacol. 2022;13:902639. doi:10.3389/fphar.2022.902639.
Park JY, Kim H, Lee JH, et al. Automated immunofluorescent assay for 25-hydroxyvitamin D using AFIAS analyzer: analytical performance and clinical utility. Int J Med Sci. 2020;17(2):123–130. doi:10.7150/ijms.4857.
PubMed Central (PMC). Prevalence of vitamin D deficiency and insufficiency in chronic pancreatitis patients. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207250/.
Valley International Journal. Assessment of 25(OH)D in patients with chronic pancreatitis using AFIAS immunofluorescent analyzer. Available from: https://valleyinternational.net/index.php/ijmsci/article/view/521.
