GENOMIC APPROACHES TO UNDERSTANDING AGING AND LONGEVITY
Keywords:
Genomics, Aging, Longevity, Epigenetics, GWAS, Mitochondrial DNA, Telomeres, Genetic Regulation.Abstract
The study of aging and longevity has advanced rapidly in the genomic era, offering new insights into the molecular and genetic mechanisms that determine lifespan and the rate of biological aging. With the advent of next-generation sequencing (NGS), genome-wide association studies (GWAS), and transcriptomic profiling, scientists have identified key genes, pathways, and molecular signatures that regulate aging across different species. This paper provides an overview of the genomic approaches applied to the study of aging, explores the biological and ethical implications of extending lifespan, and highlights the potential of personalized genomic interventions for promoting healthy aging.
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