AKTGGA BOG‘LIQ GIPERKORTISIZM
Keywords:
Giperkortisizm, AKTG, Cushing kasalligi, ektopik AKTG sindromi, kortizol, endokrin tizim, gipofiz o‘simtasi, biokimyoviy diagnostika, MRI, ACTH tahlili, o‘simta markerlari.Abstract
Mazkur mavzuda adrenokortikotrop gormon (AKTG)ga bog‘liq giperkortisizmning etiologiyasi, patogenezi, klinik belgilari va diagnostika usullari yoritilgan. AKTGga bog‘liq giperkortisizm — bu gipofiz yoki ektopik manba orqali ortiqcha AKTG ishlab chiqarilishi natijasida kortizol miqdorining normadan yuqori bo‘lishi bilan kechadigan holatdir. Ushbu maqolada kasallikning Cushing kasalligi va ektopik AKTG sindromi kabi shakllari, ularning farqlari, diagnostik algoritmlari hamda zamonaviy davolash yondashuvlari ko‘rib chiqilgan. Shuningdek, AKTGga bog‘liq giperkortisizmning endokrin tizimdagi roliga alohida e’tibor qaratilgan.
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