THE ROLE OF PLATELETS IN THE PATHOGENESIS OF PRIMARY OPEN-ANGLE GLAUCOMA: INSIGHTS FROM LITERATURE REVIEW
Keywords:
POAG, vascular dysregulation, aggregation, platelets, IOPAbstract
Primary open-angle glaucoma (POAG) is a leading cause of irreversible blindness, characterized by progressive optic neuropathy. While elevated intraocular pressure (IOP) is a key factor, vascular dysregulation and ischemia contribute significantly, especially in normal-tension glaucoma (NTG). Recent studies highlight the involvement of platelets in exacerbating ocular hypoperfusion through activation, aggregation, and microvascular interactions.
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References
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